Ibuprofen doesn't treat the virus itself, but it can make you feel a lot better. In acetaminophen products available over the counter, each pill may contain 325, 500, or 650 milligrams of the drug. They differ in how and where they do this, however. doi:10.1097/MD.0000000000005578, Levque D, Santucci R, Gourieux B, Herbrecht R. Pharmacokinetic drug-drug interactions with methotrexate in oncology. You should also not take the medication for longer than 10 days for pain relief or three days for fever relief. In rheumatoid arthritis, methotrexate helps decrease the activity of the immune system. It's long been known that large doses of acetaminophen (Tylenol and generic) taken all at once can be fatal. If you have chronic medical conditions or you are taking other medications, talk to your pharmacist to be sure there are no interactions or adverse reactions that you need to know about. You should not combine pseudoephedrine with phenylephrine or other decongestants. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. TYLENOL PM Extra Strength Nighttime Pain Reliever & Sleep Aid, 500mg Acetaminophen & 25 mg Diphenhydramine HCl 4.6 (1421) Relieves minor aches and pains while helping you fall asleep and is non-habit forming when used as directed. Comparison of two different folic acid doses with methotrexate--a randomized controlled trial (FOLVARI Study). Drugs such as diclofenac ( Zorvolex) are more likely to affect the liver, so monitoring of the liver is recommended. Thank you, {{form.email}}, for signing up. Egypt Rheumatol Rehabil. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. She specializes in pediatrics and disease and infection prevention. David Ozeri, MD, is a board-certified rheumatologist from Tel Aviv, Israel specializing in arthritis, autoimmune diseases, and biologic therapies. What You Need To Know About Etodolac Interactions, What You Should Know About Azulfidine (Sulfasalazine) Interactions, Green Tea, Thyroid Disease, and Weight Loss, Aromatase Inhibitors to Prevent Breast Cancer Recurrence, Advil Cold & Sinus (Pseudoephedrine and Ibuprofen) Oral, More Arthritis Types & Related Conditions, 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Some specific NSAIDs that should be avoided while taking methotrexate include: For those with RA, which is an autoimmune disease, medication is needed to hinder the overactivity of the immune system. An alarming one in three American adults has high blood pressure. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Do not take more than one medication that contains the active ingredient acetaminophen. Use this medicine exactly as directed. If you go over the dosage of one or the other, dangerous side effects can occur. Medicine (Baltimore). No, you should not take Tylenol and NyQuil together. Adv Pharmacol Sci. A deadly prescription: combination of methotrexate and trimethoprim-sulfamethoxazole. Usually, Meloxicam and Tylenol can be taken at the same time without a problem, if needed. Yes, In the past 3 months Yes, In the past 6 months Yes, In the past year Haven't purchased but considering Don't plan to purchase This survey is being. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Avoid driving or hazardous activity until you know how Tylenol PM will affect you. Leuk Lymphoma. Get the latest in health news delivered to your inbox! Asthma, headache, insomnia and hives are also side effects of NSAIDs. Quantifying the hepatotoxic risk of alcohol consumption in patients with rheumatoid arthritis taking methotrexate. 2015 Jun 11;17(1):156. doi:10.1186/s13075-015-0668-4, EL Nouby, F.H., Fathi, N.A., Fehr, A.A.et al. However, there are serious risks of liver damage, stomach disorders, kidney failure, and even death if you take too much of either medication. Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity. Taking them together can result in an overdose of acetaminophen, which can cause liver damage. Anticonvulsants that are safe to take while on methotrexate include: Although many NSAIDs should not be taken with methotrexate because of the increased risk of liver toxicity, tromethamine (Tham) is one that can be safely taken with only a small risk of increasing the natural side effects of methotrexate alone. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. However, its important to remember to follow the recommended daily dosage for each medication. Don't double up on acetaminophen. 4.8. Johns Hopkins Arthritis Center. One such medication is chlorpromazine. 374 drugs Meloxicam - LiverTox: Clinical Research and Information on Drug-Induced Liver Injury. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Using too much acetaminophen or diphenhydramine can lead to a fatal overdose. Also call your doctor if your symptoms get worse, or if you have any redness or swelling. If youre already taking methotrexate, its also important to speak with your healthcare provider before taking any new natural health supplements or medications. What's the best sore throat medicine to use? This NSAID gel, sold as Voltaren, works well for aches and pains. are known to interact with These medications have been shown to cause adverse side effects when taken with methotrexate, including hypertension, respiratory infections, gastrointestinal distress, and headaches. But it does raise your risk of side effects. If you go over the dosage of one or the other, dangerous side effects can occur. One common group of medications that can harm your kidneys are nonsteroidal anti-inflammatory drugs ( NSAIDs ). The results showed that in people who used high-dose acetaminophen, systolic blood pressure (the top number) increased about five points more than those who took a placebo. In fact, it's usually not used for more than 10 days in a row. Medically reviewed by Drugs.com on Sep 19, 2022. stenosing peptic ulcer. Date First Available : March 8, 2010. These medications may cause some risk when taken together. Possible side effects of diphenhydramine include daytime sleepiness, confusion, constipation, dry . Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. However, this does not necessarily mean no interactions exist. Methotrexate is the first-line treatment for most people with moderate to severerheumatoid arthritis (RA). 2005 - 2023 WebMD LLC, an Internet Brands company. Methotrexate is known to cause severe drug interactions when taken with many types of medications. 2012;13:118. doi:10.1186/1465-9921-13-118. 2010;104(1):80-8. doi:10.1093/bja/aep338. To avoid overdose, never take more than 4 grams of Tylenol within 24 hours. If you do not know how much acetaminophen you can take in a day, ask your doctor or pharmacist. Only do this when specifically instructed by your healthcare provider. Always consult your healthcare provider. To name just a few: Vicks DayQuil Cold & Flu, Theraflu Severe Cold & Cough, NyQuil, Coricidin HBP Cold & Flu, and Alka-Seltzer Plus Cold & Flu. But if you take too much of it, you could experience liver or kidney damage. National Center for Biotechnology Information. Considering collagen drinks and supplements? Some people who take methotrexate will need to take folic acid supplements because the medication can diminish the amount of folate in the body. Can I take cyclobenzaprine and Tylenol together? Best Cold Medicine: OTC Treatments for Your Symptoms, What Thyroid Patients Need to Know About Decongestants, How to Treat Cold and Flu Symptoms If You Have Diabetes, What You Need to Know About Tylenol Arthritis, Sore Throat and Cough: Causes and Treatments. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 374 drugs In fact, in most cases, the combination of the two is more effective than opioids. However, it's important to remember to follow the recommended daily dosage for each medication. 2018 Jun 12;8(3):149-151. doi:10.1080/20009666.2018.1466598, Telles-Correia D, Barbosa A, Cortez-Pinto H, Campos C, Rocha NB, Machado S. Psychotropic drugs and liver disease: A critical review of pharmacokinetics and liver toxicity. Those taking methotrexate should be aware of the drug interactions and speak with their healthcare provider about the drugs or supplements they are taking prior to starting treatment with methotrexate. inflammation of the nose due to an allergy. Tylenol PM is also used to treat minor aches and pains such as headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps. Answer. Tylenol PM is not for use in treating sleeplessness without pain, or sleep problems that occur often. Do not take aspirin when you are also taking other products that contain aspirin such as Alka-Seltzer, BC Powder, Excedrin, Goody's, Lortab, and Vanquish. cbd gummy bears 1000mg 50 mg cbd gummies for sale, 2023-03-31 dog ate cbd gummies miracle leaf cbd gummy bears organix cbd gummies. Manymulti-symptom medications also contain acetaminophen and should not be taken with Tylenol or generic acetaminophen. There are not many multi-symptom medications that contain naproxen, but you should use caution and consult your healthcare provider if you are taking multi-symptom medications that contain any type of pain reliever/fever reducerespecially if it is another NSAID such as ibuprofen or aspirin. This drug should not be taken by children or teenagers recovering from chickenpox or flu-like symptoms. Additionally, it should not be combined with topical Benadryl cream. Tylenol Cold + Flu + Cough Night Liquid provides temporary relief of common cold and flu symptoms. 2021 Jul;73(7):924-939. doi: 10.1002/acr.24596. In the Special Health Report,Controlling Your Blood Pressure, find out how to keep blood pressure in a healthy range simply by making lifestyle changes, such as losing weight, increasing activity, and eating more healthfully. Interactions among Low Dose of Methotrexate and Drugs Used in the Treatment of Rheumatoid Arthritis, Pathophysiological aspects of nephropathy caused by non-steroidal anti-inflammatory drugs. No interaction has been found between the two medications so far. I had the most awful dreams each night. There is some debate about whether caffeine poses a moderate risk of adverse effects when taking methotrexate. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. Tylenol Dosage Charts (Infants & Children). Ask a doctor or pharmacist before using Tylenol PM with any other medicines, especially drugs that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Medically reviewed by Drugs.com. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Generic name: acetaminophen and diphenhydramine [a-SEET-a-MIN-oh-fen-and-DYE-fen-HYE-dra-meen] It has also been found that taking willow bark while on methotrexate could lead to adverse interactions. Helping children who are neurodiverse build friendships, Preventable liver disease is rising: What you eat and avoid counts, Easy ways to shop for healthful, cost-conscious foods. But it turns out that cumulative smaller doses that exceed the maximum daily. Naproxen should not be combined with other pain relievers unless specifically directed by your healthcare provider. Delayed elimination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. A deadly prescription: combination of methotrexate and trimethoprim-sulfamethoxazole. Summary Safety Review - Levetiracetam and Methotrexate - Assessing the Potential Risk of Drug-Drug Interaction. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Available for Android and iOS devices. doi:10.1186/s43166-020-00028-z, Humphreys JH, Warner A, Costello R, Lunt M, Verstappen SMM, Dixon WG. Acetaminophen (Tylenol) is often the pain reliever of choice for people with high blood pressure (hypertension) because most other options are types of nonsteroidal anti-inflammatory drugs like ibuprofen (Motrin, Advil) or naproxen (Naprosyn, Aleve), which can raise blood pressure. 4 But if you have liver disease or a drinking problem, even that may be too much. Can I take both Tylenol (acetaminophen) and Advil (ibuprofen)? Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. It is also possible to have an allergic reaction to Tylenol. We comply with the HONcode standard for trustworthy health information. Acetaminophen (Tylenol ) is found in many over-the-counter products. NSAIDs can be used in combination with Tylenol (acetaminophen) for moderate pain not relieved by NSAIDs alone. Whats the Difference Between Acetaminophen and Ibuprofen? To help make it a little simpler, the following is a list of some of the most common OTC cold and flu medications that are available in the U.S. Review which ones can safely be combined and which ones you shouldn't mix. Fortunately, high blood pressure is easy to detect and treat. It was horrible. Common NSAIDs include ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), and aspirin. Always consult your healthcare provider. However, some are safe to use. This report displays the potential drug interactions for the following 2 drugs: No interactions were found between meloxicam and Tylenol. Tylenol, the brand name of acetaminophen, and meloxicam, a type of NSAID, can be taken together to relieve pain and other symptoms of arthritis. Don't take meloxicam with other NSAIDs unless your healthcare provider tells you to. Do not take more acetaminophen in a day than directed. Consuming alcohol while taking acetaminophen also increases the risk of liver damage. Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen or diphenhydramine. Arthritis Res Ther. Store at room temperature away from moisture and heat. Tylenol PM. Angelica Bottaro is a professional freelance writer with over 5 years of experience. Kristina Duda, BSN, RN, CPN, has been working in healthcare since 2002. 2019 Oct;20(20):5023. doi:10.3390/ijms20205023, Patan M, Ciriaco M, Chimirri S, Ursini F, Naty S, Grembiale RD, Gallelli L, De Sarro G, Russo E. Interactions among Low Dose of Methotrexate and Drugs Used in the Treatment of Rheumatoid Arthritis. Some people may take up to 4,000 mg (milligrams) in a day if told to do so by the doctor. The Chicago Tylenol murders were a series of poisoning deaths resulting from drug tampering in the Chicago metropolitan area in 1982. Each 15-milliliter dose contains 325 milligrams of acetaminophen, a pain reliever and fever reducer, 10 milligrams of dextromethorphan HBr, a cough suppressant, 5 milligrams of phenylephrine HCl, a nasal decongestant and 6.25 milligrams of doxylamine succinate, an antihistamine. In some instances, there's also an increased risk of these problems when you first start taking the medication. Tylenol is used to treat the following conditions: Fever Muscle Pain Pain Sciatica Drug and food interactions Moderate DULoxetine food Applies to: duloxetine DULoxetine may cause liver damage, and taking it with alcohol may increase that risk. The half-life of fluoxetine ranges from 2 to 7 days. This report displays the potential drug interactions for the following 2 drugs: No interactions were found between meloxicam and Tylenol PM. Typically, taking these drugs along with methotrexate wouldnt require any change in dose or medication. A person should not. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to relieve pain and decrease inflammation. Speak to your healthcare provider about whether you should be taking folic acid to prevent the deficiency before supplementing on your own. When it comes to meloxicam, the cause of liver damage isn't clear, but it can still occur in very rare cases. 2017 May-Jun;83(3):389-392. doi:10.4103/ijdvl.IJDVL_487_16. Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial. The best thing to do before starting a new treatment is discuss all your medications and supplements thoroughly with your healthcare provider to avoid drug interactions. Can You Take Motrin and Tylenol Together? Acetaminophen is a pain reliever and a fever reducer. If you have this type of reaction, you should never again take any medicine that contains acetaminophen. Although caffeine is listed as having the ability to reduce the efficacy of methotrexate in arthritis treatment, much of the literature suggests that claim is not accurate. They include: Too much of either medication can lead to liver damage. But relying on it for more than a few nights in a row may do more harm than good. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Beyond RA, methotrexate is also used in the treatment of severe psoriasis and some types of cancer, such as breast cancer, lung cancer, lymphoma, and leukemia. Products that contain naproxen include Aleve PM, Treximet, and Vimovo. By Angelica Bottaro Arthritis Care Res (Hoboken). Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. This means that it can take anywhere from 11 to 38.5 days for the body to clear Prozac completely. High doses of acetaminophen can cause liver damage and the risk increases if you consume alcohol. Both contain acetaminophen. Tylenol PM Extra Strength Caplets contain 500mg of acetaminophen and 25mg of diphenhydramine hydrocholoride in each caplet. It took me several hours to fall asleep and when I did. Always consult your healthcare provider. Taking meloxicam with Tylenol is safe because there are no known drug interactions between the two medications. Don't miss your FREE gift. People with diabetes are often at an increased risk of liver disease and infection, and the use of methotrexate together with some diabetes medications may increase that risk even further. However, this does not necessarily mean no interactions exist. There are not as many multi-symptom medications that contain ibuprofen as compared to acetaminophen, but you should always review the labels anyway. Can I take Tylenol while taking indomethacin and can these drugs be alternated every 3 hours? Email this report to a friend, doctor, or patient. "Using Tylenol PM is generally safe and useful for temporary sleep disturbances such as jet lag or other short-term stressors in patients younger than 65. Tylenol comes in a variety of strengthsfrom 325 mg for regular Tylenol up to 650 mg for Tylenol 8-Hour Arthritis Pain. Drinking in moderation means having no more than three drinks per . This survey is being conducted by the WebMD marketing sciences department. Although it is generally safe to take meloxicam and Tylenol together, always consult with your doctor before you start any new medication to ensure that it is safe for you given your health and medication history. However, in some cases, your healthcare provider may recommend alternating between acetaminophen and ibuprofen in three-hour intervals. No, you should not take Tylenol and NyQuil together. Some common medications that contain guaifenesin include Tussin, Equate Tussin DM, Robitussin Cough + Chest Congestion DM, Vicks DayQuil, and Zicam. Other symptoms that may be present if your liver is damaged from the overuse of acetaminophen are: If you experience any of these symptoms and believe you took too much Tylenol, seek medical care immediately. Copyright 1996-2023 Cerner Multum, Inc. Examples include NyQuil, Tylenol Cold Multi-Symptom, Alka-Seltzer Plus, and Robitussin Multi-Symptom, among many others. Is Discontinued By Manufacturer : No. Can Sudafed and DayQuil be taken together? For example, azathioprine (Imuran, Azasan) is an immunosuppressant that can be taken with methotrexate safely and effectively. Dhir V, Sandhu A, Kaur J, Pinto B, Kumar P, Kaur P, Gupta N, Sood A, Sharma A, Sharma S. Comparison of two different folic acid doses with methotrexate--a randomized controlled trial (FOLVARI Study). Skip any missed dose if it's almost time for your next dose. It may also be given to relieve pain associated with juvenile arthritis in. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. What is paracetamol / panadol called in the US? Meloxicam and Tylenol work equally well on pain. 3. Using methotrexate over a long period of time has also been linked to liver conditions such as cirrhosis. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Jenny Sweigard, MD, is a board-certified physician involved in patient care, including general medicine and critical care medicine. Speak to your healthcare provider about any possible immunizations you can and cannot receive. National Center for Biotechnology Information. The chances of a serious reaction are greater if you have a pre-existing heart condition. Methotrexate Drug Information Sheet. Always read the label of every medication you take. Some cold medications can be taken at the same time without issue, but other combinations can pose safety concerns. Stick to recommended doses. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Tylenol is in the drug class miscellaneous analgesics . Merziuz: q4gZff http://pills2sale.com/fTr1bYnau88IsQx: 2020/12/12: Jimmi: good material thanks <a href="https://denled2018.com/aldara-online-usa-cazf">aldara creme . overactive thyroid gland. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Do not use the medicine to make a child sleepy. Tylenol Dosage Charts (Infants & Children). The U.S. Food and Drug Administration warns of the danger of accidentally overdosing on acetaminophen when taking multiple OTC cold and flu medications that contain it. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. No alcohol/food interactions were found. Zarif Najafi H, Oshagh M, Salehi P, Babanouri N, Torkan S. Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. The following symptoms should be addressed by your healthcare provider immediately: Taking too much acetaminophen can lead to severe liver damage, especially if it is taken with other medications that can damage the liver. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. NSAIDs like Meloxicam relieve pain by blocking COX. Health Alerts from Harvard Medical School. Can I take Tylenol and NyQuil together? Consult your healthcare provider about the safety of these products for children age 4 and over. Ask a doctor before using this medicine if you are pregnant or breastfeeding. The CDC warns that OTC cough and cold medicines should not be given to a child younger than 4 years unless directed by their healthcare provider. Do not use this medicine for longer than 2 weeks to treat sleep problems, or longer than 7 days to treat cold or allergy symptoms. She has been educated in both psychology and journalism, and her dual education has given her the research and writing skills needed to deliver sound and engaging content in the health space. However, this does not necessarily mean no interactions exist. Tylenol. Medications that don't mix well with Tylenol. Since low doses of methotrexate are typically used to treat inflammatory arthritis like RA, the interaction with NSAIDS is typically not clinically significant. Specific medications that should be avoided or used with caution include: For those taking diuretics, methotrexate may pose a moderate risk because methotrexate may hinder the actions of the diuretic medication, diminishing its therapeutic effect. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Although taking Tylenol and prednisone together is not known to cause any negative interactions, they can interact with some other medications. Your reactions could be impaired. Benadryl should not be combined with other antihistamines unless specifically instructed by your healthcare provider. But a study in the Feb. 8, 2022, issue of Circulation suggests acetaminophen might have the same effect. Minimally clinically significant. Take 2 caplets every 8 hours. For Extended Release Arthritis & Joint Pain Relief, 650mg Acetaminophen. Do not use two doses at one time. Delayed elimination of methotrexate by cola beverages in a pediatric acute lymphoblastic leukemia population. Minimally clinically significant. Taking them together can result in an overdose of acetaminophen, which can cause liver damage. Mixing acetaminophen (Tylenol) and alcohol. Asthma, headache, insomnia and hives are also side effects of NSAIDs. However, this does not necessarily mean no interactions exist. Because NSAIDS can affect kidney function and methotrexate is metabolized by the kidney, monitoring of the creatinine is recommended. Meloxicam is only available with a doctor's prescription. Common side effects of Tylenol PM may include: This is not a complete list of side effects and others may occur. He previously served as executive editor for UCLA Healths Healthy Years and as a contributor to Duke Medicines Health News and Weill Cornell Medical Colleges. Some mixtures of medications can lead to serious and even fatal consequences. What medications cause liver enzymes to be elevated? Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, AGENTS THAT AFFECT IODIDE/RADIOACTIVE IODIDE, ANTICHOLINERGICS/SOLID ORAL POTASSIUM CAPSULES, ANTICHOLINERGICS/SOLID ORAL POTASSIUM TABLETS, SELECTED WEAK CYP2D6 INHIBITORS/TAMOXIFEN, 7 Tips to Help Control Ulcerative Colitis Flares, Treating Psoriatic Arthritis With Ixekizumab: What to Know, List Tylenol PM Oral side effects by likelihood and severity. Anita Chandrasekaran, MD, MPH, is board-certified in internal medicine and rheumatology and currently works as a rheumatologist at Hartford Healthcare Medical Group in Connecticut. In some cases, serious side effects can occur while taking your regular dosage of meloxicam. DayQuil contains phenylephrine, which is also a decongestant. That means it can reduce pain and inflammation without irritation of the stomach lining or an increased risk of stomach ulcers. Acetaminophen is a pain reliever and a fever reducer. Tylenol should not be combined with other pain relievers/fever reducers unless you are specifically instructed to do so by a healthcare provider. Importantly, Tylenol is available over the counter without a prescription. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. These interactions are not as dangerous as those above, but they do pose health risks. Cleveland Clinic. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Both contain acetaminophen. Stay on top of latest health news from Harvard Medical School. Can I take Meloxicam and Aleve or Tylenol together? Some specific diuretics that you should look out for when taking or starting methotrexate include: Methotrexate has been reported as a seizure inducer and should be avoided by most on antiepileptic drugs. 2015 Oct;16(34) doi:10.1186/s40510-015-0104-y, Yoon E, Babar A, Choudhary M, Kutner M, Pyrsopoulos N. Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update. Some mixtures of medications can lead to serious and even fatal consequences. We comply with the HONcode standard for trustworthy health information. Key takeaways: Tramadol (Ultram, ConZip, Qdolo) is an opioid medication used to treat pain.